The characteristics of the peripheral transport of C14-labeled palmitic acid.

The portal transport of absorbed fatty acids.

Earlier reports have shown that absorbed U4-labeled stearic (l), palmitic (2), and pentadecanoic (3) acids can be recovered, almost quantitatively, in intestinal or thoracic duct lymph. In the case of myristic acid, however, the highest recovery in lymph was about 80, and the lowest about 60 per cent of the absorbed C14. Still lower values (15 to 55 per cent) were observed with lauric acid, and...

The role of unesterified fatty acid transport in chylomicron metabolism.

In a study to determine the early fate of absorbed fat, previously reported from this laboratory, observations were made on the removal of chylomicra containing triglyceride labeled with palmitic acid-l-C14 from the plasma of the anesthetized dog (1). It was found that the triglyceride fatty acids (TGFA) rapidly appeared in the albumin-bound unesterified fatty acid fraction (UFA) of the plasma....

Intestinal lymph as pathway for transport of absorbed fatty acids of different chain lengths.

ECENT studies with C14-labeled palmitic and pentadecanoic acids have shown R that, after their absorption, these fatty acids can be recovered almost quantitatively from intestinal or thoracic duct lymph (I, 2). Since there are indications in the literature that a short-chain fatty acid, such as butyric, does not, to any appreciable extent, make use of lymph (3), we have inquired into the specif...

The metabolism of chylomicra. I. The removal of palmitic acid-1-C14 labeled chylomicra from dog plasma.

Incorporation of Fatty Acids into Phospholipids of Erythrocyte Membranes.

Incorporation of C14-labeled fatty acids into phospholipids by washed ghosts, prepared from human erythrocytes, required the addition of ATP and was markedly stimulated by MgC12 and coenzyme A. Labeled palmitic acid from l-C"-palmitoyl CoA was incorporated in the absence of added cofactors, The extent of incorporation of linoleic acid was greater than that of oleic, palmitic, or stearic acids. ...